NEWS
ldsep 2.1.5 (2022-10-18)
- Bug fix: Use
&&
instead of &
in C++ source.
ldsep 2.1.4 (2022-02-11)
- Use unnamed formula argument in
aggregate()
to account for change in R.
ldsep 2.1.2 (2021-08-10)
DOUBLE_EPS
-> DOUBLE_EPSILON
.
- Modified citation to point to Heredity.
- Adds notes about the necessity of using adaptive priors in
ldfast()
.
ldsep 2.1.0 (2021-06-11)
- Includes a
win
argument in ldfast()
, which implements the moment-based LD correction along a sliding window.
- Fixes a bug where monomorphic SNPs were causing errors when
type = "Dprime"
was selected in ldfast()
. Now we just return NA
's for LD with monomorphic SNPs.
- Uses the complete reference of Gerard (2021) (doi:10.1111/1755-0998.13349)
ldsep 2.0.2 (2021-02-17)
- Removes
ldfast_old()
and ldfast_calc()
, which were not used in any
exported functions, because these functions had memory issues, detected
by valgrind.
ldsep 2.0.1 (2021-02-12)
- Added
ldfast()
, a new LD estimation approach based on sample
moments of marginal posterior genotype moments.
- Unlike
ldest()
, mldest()
, and sldest()
, the new approach
implemented in ldfast()
is scalable to genome-wide applications,
as these new estimators can be calculated in linear time in the
sample size.
- Citation of MLE approach points to MER article.
ldsep 1.1.0 (2020-11-14)
- I have changed the terminology from "gametic LD" to "haplotypic" LD,
and so all instances of "gametic" have changed to "haplotypic". A breaking
change is that all options that were
"gam"
are now "hap"
.
- Fixed an issue where the title in
plot.lddf()
was being cut off.
- Added a reference to the preprint where the methodology is developed.
- Updated the vignette to also take a user through uploading a VCF file
into R using the
VariantAnnotation
package. We also provided
examples on formatting genotype likelihoods from updog
and
fitpoly
.
ldsep 1.0.0 (2020-08-02)
- Initial release of package.