Package: seqgendiff Type: Package Title: RNA-Seq Generation/Modification for Simulation Version: 1.2.4 Authors@R: person("David", "Gerard", email = "gerard.1787@gmail.com", role = c("aut", "cre"), comment = c(ORCID = "0000-0001-9450-5023")) Description: Generates/modifies RNA-seq data for use in simulations. We provide a suite of functions that will add a known amount of signal to a real RNA-seq dataset. The advantage of using this approach over simulating under a theoretical distribution is that common/annoying aspects of the data are more preserved, giving a more realistic evaluation of your method. The main functions are select_counts(), thin_diff(), thin_lib(), thin_gene(), thin_2group(), thin_all(), and effective_cor(). See Gerard (2020) for details on the implemented methods. License: GPL-3 Encoding: UTF-8 URL: https://github.com/dcgerard/seqgendiff BugReports: https://github.com/dcgerard/seqgendiff/issues RoxygenNote: 7.3.1 Suggests: covr, testthat (>= 2.1.0), SummarizedExperiment, DESeq2, knitr, rmarkdown, airway, limma, qvalue, edgeR Imports: assertthat, irlba, sva, pdist, matchingR, clue VignetteBuilder: knitr Config/pak/sysreqs: libpng-dev libxml2-dev libssl-dev zlib1g-dev Repository: https://dcgerard.r-universe.dev Date/Publication: 2024-05-15 09:43:42 UTC RemoteUrl: https://github.com/dcgerard/seqgendiff RemoteRef: HEAD RemoteSha: 9629ad951b355c23e5e9a11cff59f6b90d65b188 NeedsCompilation: no Packaged: 2026-06-06 06:59:35 UTC; root Author: David Gerard [aut, cre] (ORCID: ) Maintainer: David Gerard